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Transdermal and Oral Hormone Replacement Therapy and the Risk of Stroke: A Nested Case-Control Study BMJ 340:c2519, Renoux,C., et al, 2010 See this aricle in Pubmed Article Abstract The use of transdermal HRT containing low doses of oestrogen does not seem to increase the risk of stroke. The presence of residual confounding, however, cannot be entirely excluded in the interpretation of this finding.

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